No One Is More Disappointed In Me Than I Am.

No one is more disappointed in me than I am.

More Posts from Muahahahahah and Others

5 years ago

In case it’s helpful - here’s a link to Marsha Linehan’s full DBT Skills Training Handouts & Worksheets. These have helped me a phenomenal amount & idk, I hope they might help some of you.

5 years ago
Sun Cat. 7 X 5 Inches, Oil On Hardboard.

Sun Cat. 7 x 5 inches, oil on hardboard.

6 years ago
Nick Cave Talking About The Death Of His Son, Arthur
Nick Cave Talking About The Death Of His Son, Arthur
Nick Cave Talking About The Death Of His Son, Arthur
Nick Cave Talking About The Death Of His Son, Arthur
Nick Cave Talking About The Death Of His Son, Arthur
Nick Cave Talking About The Death Of His Son, Arthur

Nick Cave talking about the death of his son, Arthur

One More Time with Feeling (2016) dir. Andrew Dominik

2 months ago

If you don’t experience the pain that I do every day, you don’t get to judge me.

Not my food habits.

Not my hygiene.

Not my productivity.

Not the clothes I wear.

Not my outlook on life.

Not my goals.

Not my medications.

Not my weight.

Not your body!

You don’t get to decide if I have a moral failing because you think you’re better than me and you could handle it better. Please, try to experience one day of pain like mine. Try to experience one week.

When you’re faced with the choice of not eating and ordering fast food, it’s an easy choice. You choose to eat.

When you’re faced with passing out or wiping yourself down with baby wipes, it’s an easy choice. You choose to be safe.

I am sick of the lectures about what’s good for me, the dangers of seed oils, how medication is propaganda from big pharma, how I’m just lazy and I can take a damn shower.

IT’S NOT YOUR BODY, so get out of my business.

6 years ago
Elizabeth Debicki And Gemma Arterton As Virginia Woolf And Vita Sackville-west In Vita & Virginia (2019),
Elizabeth Debicki And Gemma Arterton As Virginia Woolf And Vita Sackville-west In Vita & Virginia (2019),
Elizabeth Debicki And Gemma Arterton As Virginia Woolf And Vita Sackville-west In Vita & Virginia (2019),
Elizabeth Debicki And Gemma Arterton As Virginia Woolf And Vita Sackville-west In Vita & Virginia (2019),
Elizabeth Debicki And Gemma Arterton As Virginia Woolf And Vita Sackville-west In Vita & Virginia (2019),
Elizabeth Debicki And Gemma Arterton As Virginia Woolf And Vita Sackville-west In Vita & Virginia (2019),

Elizabeth Debicki and Gemma Arterton as Virginia Woolf and Vita Sackville-west in Vita & Virginia (2019), with excerpts from Virginia and Vita’s love letters.

6 years ago

Jo I’m crying

We (germany) had a comedian party to vote for the european election and a guy named Nico Semsrott will be in the parlaiment

He makes commedy about depression and his show was called “happiness is just a lack of information” this cracks me the fuck up hahaha I love that dude

5 years ago

Neuroscience of BPD

Lately I’ve been hearing that BPD isn’t a real mental illness because nothing is actually wrong with our brains and so, naturally, that means we’re using BPD as an excuse for our mood instability and impulsive behavior.

Guess what, naysayers? You were COMPLETELY right and totally called us out on our nefarious scheme!! We did, in fact, all convene at a super secret BPD convention of sorts and plotted to infiltrate the psychiatric field.

Haha, no. With the help of alix660 and porcelaindissonance I’ve learned a lot about the neuroscience behind BPD. And, while much more needs to be done in terms of BPD research, I did find strong evidence that BPD does have biological causes. You know. Just like an actual mental illness.

So here’s what we found, sorted by brain structure:

Amygdala: This brain structure is very heavily involved in emotional regulation and responses, particularly negative emotions. An fMRI study of BPD patients while being subjective to distressing visual stimuli found that our amydalas were significantly more reactive than those of control patients. This means that either the signals in our amgydalas are much more intense, or they continuing firing in our brains, preventing us from shutting down our emotional responses. Or perhaps it’s both, because that’s fun.

Another thing to note is that the amygdala receives tons of visual information, sent by the thalamus. The thalamus circumvents emotional processing in the prefrontal cortex (where we would consciously process how to regulate our emotions) and thus is involved in automatic, subconscious emotional processing. This is probably why our mood swings are so fast, unpredictable, and uncontrollable. It’s a knee-jerk reaction to even the tiniest triggers we come across.  (Herpetz, et al.)

Amygdala volume is significantly reduced in BPD patients as well. (van Elst, et al.)

Hippocampus: This structure is involved in formation and retention of long-term memories, as well as autobiographical memories. Not only is hippocampal volume reduced in PTSD and MDD, it is also reduced in BPD. (van Elst, et al.)

I know from my studies that the reason for hippocampal volume reduction in PTSD and MDD comes from prolonged activation of the stress response. When we go into “fight or flight” mode, several physiological changes take place: our immune system shuts down, digestion stops, etc. But most importantly, when we enter “fight or flight,” glucose, which is necessary for cell metabolism, is redirected from the hippocampus and to your muscles. If you’re faced by a life-challenging thing, like a pack of velociraptors, you don’t want to think about it. You want to run, and you want to run fast. This is biologically adaptive in the short-term and in prey species… but not so with humans, because we can have this reaction to long-term, non-threatening stressors. So in long-term distress—like MDD, PTSD, and BPD—our hippocampus is starved of energy and atrophies. Result? We have absolutely terrible memory.

Prefrontal cortex: This is where we do our conscious thinking. More specifically, the medial prefrontal cortex, which is involved in processing emotional memories, is more active in the BPD brain. Essentially, this means we have difficulty mediating our conscious emotional responses.

In the ventrolateral prefrontal cortex, BPD brains also show abnormally high reactivity to aversive stimuli. This part of the cortex directly connects to our good friend the amygdala, and thus has some level of control over emotion-driven responses. (Herpetz, et al.)

In the anterior cingulate cortex, which is involved in feelings of apathy and emptiness, we see a significant reduction in volume in the BPD brain. The ACC is linked to self-harm and pain sensation. (van Elst, et al.)

In the orbitofrontal cortex, we also see volume reduction in BPD. The OFC is responsible for irritability, impulsivity, and instability, which are our favorite things.

Fusiform gyrus: Found in the temporal lobe, the fusiform gyrus is the facial recognition center of the brain. And—you guessed it—it’s also shown to be hyperactive in the BPD brain. Which makes sense when you think about it: we are EXTREMELY sensitive to even the slightest changes in the facial expressions of other people. If you appear disinterested, annoyed, angry, or otherwise upset, that’s an immediate trigger. (Herpetz, et al.)

Taken together, this means that the limbic circuits (emotional regulation) and the prefrontal cortex (executive control) are uniquely involved in BPD, resulting in a hyperarousal-dyscontrol syndrome. As of right now, no other psychiatric illness has this combination of reduced brain structure volumes and hyperactivity in certain regions. (van Elst, et al.)

Bonus!!!

Serotonin: Most of us know serotonin as a crucial neurotransmitter involved in major depressive disorder. But in BPD, studies show that reduced serotonin activity is found in several locations in the brain, including the cingulate cortex, which is critical in processing incoming emotional cues. Reduced serotonin impairs inhibition of aggressive behaviors, both directed at others (like outbursts) and directed at the self (like self-harm and self-hatred). Genes involved in serotonin can easily be studied. (Skodol, et al.)

Sources:

Skodol, et al. “The Borderline Diagnosis II: Biology, Genetics, and Clinical Course”

Herpetz, et al. “Evidence of Abnormal Amygdala Functioning in Borderline Personality Disorder: A Functional MRI Study”

van Elst, et al. “Frontolimbic Brain Abnormalities in Patients with Borderline Personality Disorder: A Volumetric Magnetic Resonance Imaging Study”

PS I did read several other articles that corroborated these findings, so it’s not like these are the only sources of evidence I found that point to the biological nature of BPD.

7 years ago

I should have killed myself~

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muahahahahah - Muah-Ha-Ha
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