Pura Lempuyang Door By Gophrette Power

Sometimes I get lucky on the rotovap and end up with beautiful crystals.

(I am now realizing that all of my coolest chem lab pictures are related to crystallization...)

Louise Langgaard | See more work

just science things

searching for half an hour for that one paper you read 10 fucking months ago but forgot to save and it’s the only one with the data you really want to include in your grant/paper/presentation

doctor: looks like we'll have to perform a CAT scan. is this something you're familiar with?

me: I've spent my whole life scanning my environment for cats

it he @ultrainfinitepit

Introducing the most versatile piece of laboratory equipment: the septum. It’s a septum! It’s a makeshift SureSeal! It’s a makeshift vial adapter! It’s a holder for reaction tubes!

Amber Ibarreche

CRISPR/Cas Just Got About One Hundred Million Dollars Hotter

CRISPR Therapeutics and Vertex Pharmaceuticals Incorporated announced  that they will be entering into a 105 million USD strategic research collaboration focused on developing therapeutics for genetic disease.

In more detail, what does that mean? A number of genetic mutations are responsible for inherited diseases, and two examples of this are cystic fibrosis and sickle cell anaemia.

Cystic fibrosis (CF) is caused by mutations within the CFTR gene which lead to a broken or non-folding protein, this in turn prevents the proper dilution of mucosal secretions and thus leads to numerous pathologies. Sickle cell anaemia/disease, by contrast, is due to mutations within the gene coding for haemoglobin leading to protein aggregation and disruption of red blood cell structures. It is predominantly found in descendants from malaria-prone areas, as the mutation – at least in heterozygotes – provides innate resistance against malarial infection.

The collaboration between Vertex and CRISPR will initially focus on developing therapeutics for cystic fibrosis and sickle cell anaemia, with other unspecified genes also on the target list

Full Story: Syniobeta

The Harvard Computers (Hint: They were women, not machines!)

Today is the birthday of Annie Jump Cannon, born December 11, 1863, known as one of ‘Harvard’s Computers’. She is credited along with Edward Pickering as the creator of the Harvard Classification Scheme which remains the foundation of today’s stellar classification system.

One of a dozen women hired by Pickering to do the hard work of identifying, classifying and cataloging hundreds of stellar objects, Cannon distinguished herself as the brightest of the bright and rose finally to a full professorship before her death in 1941. Pickering hired the first of his ‘computers’ in a pique of frustration, noting that his maid could probably do better work than he was getting from his students.  Indeed, he hired his maid, Williamina Fleming, who became the first of his ‘computers’ and quickly distinguished herself. Pickering was pleased enough with her work (and lower wages) that he soon built a team comprised entirely of women to compose the catalog. Cannon was hired a little later to oversee a catalog of the southern skies.  While no eponym celebrates her name, her contribution (along with the remaining group at Harvard) as well as the countless women throughout history to impact science, math, politics and all human endeavor, today we remember and say Happy Birthday. A true gifted scientist and true pioneer, gone but not forgotten. As in most human endeavors, nameless and tireless women support the work of more celebrated men with little or no credit.  Newton said of his work:  ’If I have seen further it is by standing on the shoulders of giants.’  Today we acknowledge that many of those giants were and are women.

Image curently in the public domain courtesy New York World-Telegram and the Sun Newspaper.

Today’s post is for hb-she does twice the work and asks for half the credit.  Our boys are who they are because of her.