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The #1 PlayStation 2 emulator, PCSX2, recently received a significant update. It was practically re-written from the ground up! And it now uses a similar UI as DuckStation. You can grab it from its homepage: https://pcsx2.net/
I rewrote my PCSX2 tutorial to reflect the new version: https://fantasyanime.com/emuhelp/pcsx2
One improvement that I quickly noticed was PCSX2 no longer shows obstructive artifacts when you upscale the resolution. Now it just works.
Left: Artifacts in PCSX2 v1 Right: Upscaled resolution in PCSX2 v2 with no issues